Reviewing variants

The Variant Interpreter organizes findings by variant class, each on its own tab, because each class is called by a different method and evaluated with different evidence. Use the page that matches what you're reviewing:

• Small variants (SNVs & indels)

• Structural variants

• Copy number

• Tandem repeats

• Paralogs

Every tab shares the same pattern: a filtered variant list, with visualizations where the class benefits from them, and a detail view where you explore the affected gene, review its annotation panels, open the genome browser (IGV), and classify the variant. Classifying a variant makes it eligible for the report. The sample drawer is available on every tab for context.

Across every class, the workflow has already applied a population-frequency filter so that common variants are removed before you review. How that filter is set is described in Filtering & prioritization.